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Virtually all patients with PD experience some mood disturbance during the course of the disease. This is not surprising.


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Like any other chronic condition, PD poses many daunting challenges on a daily basis and these can be discouraging to both the patient and his or her family. It is entirely normal to go through periods of sadness and discouragement. It is also entirely normal to experience worry and anxiety about how you and your family are going to cope with all the curve balls PD throws at you.

Non-Motor Symptoms of Parkinson's Disease

So sadness and anxiety are entirely normal reactions to PD. What gets worrisome and requires attention is when the sadness turns into depression or when the anxiety becomes persistent and interferes with daily functioning. The speech problems of PD include difficulty with the articulation of speech sounds, speech volume, and speech prosody or melody. These may sound like small problems but they can have a huge impact on your daily social interactions so it is important to treat these problems as soon as you can.

Dopamine supplies those areas of the brain that are particularly important for concentration, reasoning, reflecting and planning. But that small slowing can have big effects on functioning if left untreated. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life.


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  • More in Parkinson's Disease. Most of these individuals do not feel refreshed after awakening from sleep. Insomnia in PD is related to muscle cramps, immobility, frequent need to get up and urinate, anxiety and side effects of medication. Many PD patients experience intense daytime fatigue and sleepiness. We do not yet have firm numbers on how many patients experience daytime sleepiness. Daytime sleepiness may be dangerous if the patient needs to do a lot of driving.

    Excessive daytime sleepiness in PD may be due to a variety of factors including insomnia, sleep apnea see below , depression and drug therapy the dopamine agonists, in particular, may cause sleepiness. Sleep apnea refers to a significant difficulty with breathing during sleep. Sleep apnea is a major cause of nighttime insomnia and daytime sleepiness. Surgical Oncology. Transplant Surgery.

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    OSHs in Surgery. Non-motor Symptoms of Parkinson's Disease 2 ed. Edited by K. Schapira, and Werner Poewe Abstract Patients with Parkinson's disease PD are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms NMS that are often present before diagnosis or that inevitably emerge with disease progression. Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls Marcus M.

    Anna Sauerbier Peter Jenner Vanesa Bellou Lazaros Belbasis Karina Lebel Christian Duval Robert A. Hauser Stuart H. David Wilkinson Aleksandra Podlewska Lina Wang Min Wang Most Cited Articles The most cited articles published since , extracted from Scopus. Marcus M.

    Special Issues. Vincenzo Bonifati Hubert Fernandez Kathi Kemper. Zbigniew Wszolek Vincenzo Bonifati PlumX Metrics. Below is a recent list of — articles that have had the most social media attention. The Plum Print next to each article shows the relative activity in each of these categories of metrics: Captures, Mentions, Social Media and Citations.